Wednesday 27th June 2018

9:00 Welcome speech by :

Roger Genet (President of DIM1HEALTH CA)

Roger Le Grand (IDMIT) and Pascal Boireau (DIM1Health)

Anne Flury-Hérard (Head of François Jacob Institute of Biology)

9:45-13:05 Session 1 Infections and environment

Chairs: Jeffrey Lifson, Jean Estebanez, Françoise Botterel-Chartier

Anavaj SAKUNTABHAI Institut Pasteur, Functional Genetics of Infectious Diseases, France

Martine PEETERS IRD, Inserm U1175, UMI 233, Translational research on HIV and infectious diseases, France

Jan HELLERT, “Structural basis for Orthobunyavirus neutralization” Institut Pasteur, Structural Virology, France

Mathieu PICARDEAU, “Leptospirosis, a forgotten but emerging zoonotic disease” Institut Pasteur, Biology of Spirochetes unit, France

J. Pablo RADICELLA, “Exploring the early steps of natural transformation in Helicobacter pylori, a key process in the spreading of antibiotic resistances” CEA, UMR967 CEA/INSERM, France

Luca FREDDI, “The glutaminase-dependent system confers extreme Acid Resistance to new species and atypical strains of Brucella” Centre d'études d'agents Pathogènes et Biotechnologies pour la Santé, UMR 5236, France

Thierry NAAS, “Genes without frontiers and pandrug-resistant Escherichia coli isolates” APHP, Hôpital Bicêtre Service de Bactériologie, France

13:05-14:15 Lunch and poster session

14:15-17:30 Session 2 Transmission and physiopathology

Chairs: Guido Silvestri, Evelyne Jouvin-Marche, Daniel Candotti

Constantinos PETROVAS, “Visualizing Immunity: lessons from HIV/SIV studies” NIH, Immunology Laboratory, USA

Mirko PAIARDINI Emory University, Yerkes National Primate Research Center, USA

Philippe GRELLIER MNHN, CNRS UMR7245, "Inactivation of pathogens in blood supply for transfusion", Team Biodiversity and Adaptation of Eukaryotic Microorganisms to their Environment, France

Neil BERRY, “Comparing the susceptibility of New and Old World Monkeys to infection with Zika and the potential of Convalescent Serum to Protect” NIBSC, Division of Virology, UK

 Nicolas HUOT, “MHC-E restricted control of NK cells in response to SIVagm infection” Institut Pasteur, HIPER, France

 Luis MONTANER, “CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells” The Wistar Institute, USA

Florence BUSEYNE, “Clinical signs and blood-test results of humans infected with zoonotic simian foamy viruses: a case-control study” Institut Pasteur, UEPVO, France

Thursday 28th June 2018

9:30-12:30 Session 3 Vaccines

Chairs: Camille Locht, Gabriella Scarlatti, Rémi Cheynier

Keith REEVES, “Memory and memory-like NK cell responses against HIV/SIV infections and vaccines”

Beth Israel Deaconess Medical Center - Harvard Medical School, Center for Virology and Vaccine Research, USA

Olivier SILVIE, “Malaria liver infection: searching for novel vaccine targets in Plasmodium sporozoites”

INSERM, UPMC UMRS CR7, U1135, Molecular Biology and Immunology of Malaria Liver Infection, France

Frédéric TANGY,  Instiut Pasteur, UMR3569 Génomique Virale et Vaccination

Jean-Louis PALGEN, “Innate responses to vaccine differ at each immunization” CEA, IMVA/IDMIT U1184, France

Olivier BOURRY, “Evaluation of mucosal influenza A virus vaccination in the swine model” ANSES, Laboratoire de Ploufragan-Plouzané, France

Karunasinee SUPHAPHIPHAT, “A combination of broad neutralizing antibodies efficiently protects from in vitro cell-associated SHIV162P3 transmission” CEA, IMVA/IDMIT U1184, France

12:30-14:00 Lunch and poster session

14:00- 17:00 Session 4 Innovative treatments

Chairs: Sabine Riffault, Jan Langermans,Guido Silvestri

Jean-Luc TEILLAUD INSERM, UMRS 1138, Cancer, Immune control, and Escape, France

Elias FATTAL University Paris-Sud, "Nanomedicines for targeted drug delivery", School of Pharmacy, Particle and cell engineering for therapeutic applications, France

Stephen KENT, “Anti-influenza hyperimmune immunoglobulin enhances Fc-functional antibody immunity during severe human influenza infection” University of Melbourne, Australia

Philippe LOISEAU, “Antileishmanial drugs targeting host cell vesicular trafficking: toward a drug candidate” Université Paris-Saclay, UMR8076 BioCIS, France

Carmen GALLEGO, “Role of CXCR7 chemokine receptor in human papillomavirus life cycle and carcinogenesis” Université Paris-Saclay, UMR996 Inflammation, Chemokines and Immunopathology, France

Grégory CAIGNARD, “Virus-host interactome high-throughput mapping: from the identification of new factors of pathogenicity and interspecies transmission to new therapeutic targets for an animal arbovirus” ENVA, UMR1161 Virology, France

Olga SOUTOURINA, “Regulatory RNAs in the human pathogen Clostridium difficile: identification of new type I toxin-antitoxin systems associated with CRISPR arrays” CEA, UMR9198, France

17:00 Closing remarks by Roger Le Grand and Pascal Boireau